Lilly To Bolster IBD Pipeline With $3.2bn Morphic Bid

 
• By Joseph Haas
  
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With only one inflammatory bowel disease product, Lilly is betting big on Morphic and its Phase II oral integrin MORF-057, which would directly compete with Takeda blockbuster Entyvio.

Eli Lilly logo sign atop Lilly Biotechnology Center campus
Lilly will add oral integrins to its pipeline via $3.2bn bid for Morphic • Source: Shutterstock

Already a major player in integrin therapy for diabetes and obesity with Mounjaro/Zepbound (tirzepatide), Eli Lilly and Company now is looking to that drug class to add critical mass in gastrointestinal disease, announcing a $3.2bn bid on 8 July to acquire Morphic Therapeutic, Inc. and its Phase II MORF-057, an oral alpha-four/beta-7 (α4β7)-targeting compound in development for ulcerative colitis and Crohn’s disease.

Lilly is wagering that Morphic’s candidate will offer an efficacy and safety profile sufficient to compete with Takeda Pharmaceutical...

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