Legal & IP

Scrip-Business (Free-1): Top-Selling Drugs 2024: Keytruda, Ozempic And Dupixent Dominate

 
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Merck’s immuno-oncology blockbuster was the world’s best-selling drugs by revenues for the second year in a row, with an almost $12bn lead over its closest rival, Novo Nordisk’s GLP-1 drug Ozempic.

MSN Put On Hold As DC Appeals Court Freezes Generic Entresto Approval

 
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MSN Laboratories will be unable to move forward – for now – with any potential ‘at-risk’ launch for its generic version of Novartis’ Entresto blockbuster in the US after the originator won a stay on the firm’s ANDA pending appeal from the US Court of Appeals for the District of Columbia Circuit.

Investors Hit The Alarm Bells As Indivior Issues Profit Warning

 
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The UK group remains confident that the scale of the US opioid epidemic, driven by misuse of fentanyl, still represents a considerable opportunity but investors have reacted nervously to lower revenues coming from Sublocade.

SCOTUS' Mifepristone Decision Sets High Bar For US FDA Suits

 

The unanimous decision that the Alliance for Hippocratic Medicine lacks standing to challenge the FDA’s relaxation of the abortion pill REMS leaves unclear whether the court would have deferred to the agency’s expertise on the merits. 


Quick Listen: Scrip's Five Must-Know Things

 
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In this week's podcast edition of Five Must-Know Things: Biogen’s immunology acquisition; AstraZeneca looks to cement respiratory lead; why US FTC is tough on pharma; the US election’s impact on pharma; and how new AI tools are impacting medical affairs. 

China Biotech Podcast: BIOSECURE Markup, Biotech Pipeline Updates

 

As the proposed US BIOSECURE Act heads to a full House Oversight Committee vote, Scrip's China-based editors Brian Yang and Dexter Yan, together and guest Derrick Gingery from the Pink Sheet, discuss the implications and potential outcomes for the biopharma sector and factors behind the "biotech decoupling" trend. Dexter also shares insights from his recent coverage of antibody-drug conjugate R&D updates by Chinese companies.

Vaccine Star's Surprise Downfall Indicative Of Trouble In China’s COVID Push?

 
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Apparently months after his actual detention, news has finally surfaced that a key researcher behind China's rapid development of a homegrown COVID-19 vaccine is said to have "severely violated" Communist Party rules and regulations and is the subject of a probe for possible corruption.

Bolar Exemption India Files: Roche Blocks Alleged Infringer Of Evrysdi Patent

 

More legal action in India that has the Bolar exception provision at its crux with Roche, in this instance, warding off a local drug maker in the Evrysdi patent infringement case.


Pharma Firms Welcome 'Pragmatic' EU Reforms But Concerns Persist

 
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The European parliament has voted for legislation it says will lead to fairer, more accessible healthcare. The continent's drugmakers are still not wholly convinced.

All Over For Acorda After A Torrid Few Years

 
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The embattled US biotech has gone into Chapter 11 and linked up with 'stalking horse' bidder Merz which has offered $185m to get hold of Ampyra for multiple sclerosis and Parkinson’s therapy Inbrija.

Conflicts Of Interest Delay Leqembi’s EU Approval

 
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Eisai/Biogen’s Alzheimer’s drug has fallen foul of a recent court ruling over the handling of the European Medicines Agency’s experts' competing interests.    

India IPR Realities: Pharma, Legal Heads Discuss Winds Of Change, ‘Damocles Sword’

 

Leaders from Novartis, Bayer, Sun Pharma, the Indian Pharmaceutical Alliance, Médecins Sans Frontières and Anand and Anand discuss India’s evolving intellectual property rights landscape, including pre-grant oppositions, enforcement action and other realities. Concerns around evergreening, restrictions on patent-eligible subject matter and compulsory licensing were also key talking points at a recent conference in Hyderabad.


Bayer Boss Rules Out Divisions Split For Now

 
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CEO Bill Anderson says that while the troubled Leverkusen-headquartered group operates three healthy businesses, it has been "badly broken in four places.”

Share Dealings Of Ex-CEO Cast A Cloud Over Evotec

 
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The German biotech has distanced itself from recently resigned head Werner Lanthaler who appears to have violated the rules regarding the buying and selling of stock.

Biden's Latest Rx Pricing Moves Are At Once Bold And Incremental

 
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As the president’s reelection campaign themes take shape, the administration is preparing to leverage NIH patents in ways it had previously eschewed. As with the merger oversight effort, though, the germs of the plans began earlier in Biden’s tenure.

IRA Litigation Hurdles Clarified With Ruling In Chamber Of Commerce Suit

 

Drug manufacturers will have to participate in the Medicare drug price negotiation process for the foreseeable future. Judge Newman's finding that participation in Medicare is voluntary could defeat constitutional challenges to the program and have an impact on other cases. 


Hengrui, BeyondSpring In Arbitration Face-Off After Cancer Deal Setbacks

 

A Chinese court decision sheds light on how Chinese major Hengrui Medicine is seeking to reduce or avoid potential losses worth up to $27m following regulatory setbacks with the tubulin inhibitor plinabulin, in-licensed from BeyondSpring in 2021.

Amgen’s FTC Settlement To Allow $27.8bn Horizon Deal Closure Sets New M&A Precedent

 
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Amgen agreed not to include Horizon’s Tepezza and Krystexxa in rebate bundling deals with payers, among other terms, so the FTC would clear the companies’ merger, giving pharma firms a new consideration in future dealmaking.

Pfizer Facing Whistleblower Lawsuit Over China FCPA Concerns

 
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Pfizer is facing a US lawsuit alleging wrongful termination and retaliation against a whistleblower after the company’s former director of Global Compliance Analytics discovered what he viewed to be potential violations in China of the US Foreign Corrupt Practices Act.

FTC Is Ready To Negotiate Over Amgen/Horizon Merger

 
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Amgen asked the FTC to accept its pledge not to bundle Horizon’s Tepezza or Krystexxa, while an FTC administrative law judge urged a settlement between the agency and Amgen.