Drug Pricing

How A New Healthcare Dialogue Is Driving Market Access In Mexico

Companies stand a better chance of securing public reimbursement in Mexico for innovative medicines if they understand changing approaches to healthcare. The shift means the emergence of managed entry agreements and a focus on economic impact, explains AMIIF, Mexico's research-based pharmaceutical industry association.

India Rare Diseases: Court Shows Path For Policy Action, Funding, Price Issues-- Test-2

A court order encompassing funding, drug pricing, clinical trials and overall policy implementation aspects is expected to bring about a paradigm shift in the treatment of rare diseases in India. Sarepta, Roche and Sanofi are among the key players that have been part of pricing discussions.

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Nancy Tests SPARC-931 Part 8

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As More DLL3 Bispecifics Advance, Doctors Are Adjusting To CRS, ICANS

 
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Amgen’s Imdelltra for small-cell lung cancer is one of two bispecific T-cell engagers approved for solid tumors, but data at the WCLC meeting show other DLL3-targeting BiTEs may be on the way.


Novo Nordisk’s Semaglutide Shows Promise In Hidradenitis Suppurativa

 

An academic study of GLP-1 agonist showed promise in patients with the painful skin condition but with no signs that the Danish drugmaker will pursue the indication, smaller players in the space may be interested.

Merck’s Winrevair Approved For PAH In Europe As Initial US Launch Progresses

 
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Merck & Co. won European Commission approval for Winrevair on top of other medicines for pulmonary arterial hypertension and expects an initial EU launch in Germany.

Quick Listen: Scrip's Five Must-Know Things

 
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In this week's podcast edition of Five Must-Know Things: CMS’s price reveal better than expected?; new diabetes risk data for Zepbound; can J&J’s lung cancer combo stand up to Tagrisso?; new recruits for BioMarin leadership; and Glenmark’s shifting revenues.

England’s Cost Effectiveness Rejection Is Another Setback For Eisai And Biogen’s Leqembi

 

Cost watchdog NICE has blocked Leqembi’s use, but a pricing deal could unlock access to the beta-amyloid targeting drug


CMS’s Big Drug Price Reveal Turns Out Better For Pharma Than Feared

 

The first round of US government drug price negotiations resulted in prices for 10 drugs that will lower aggregate net spending by 22%

Syros’s AML Failure Sparks MDS Program Jitters, But Fears May Be Overblown

 

Discontinuation of the AML study created concern about potential readthrough to a pivotal MDS trial, but the company and analysts pointed out differences in the diseases.

Pierre Fabre Pushes To Be Partner Of Choice For Budding Biotechs

 
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Francesco Hofmann, head of R&D at the mid-sized French group, tells Scrip that its strategy of not playing in the spaces that are dominated by big pharma is paying off.

Galderma Gets First Biologic To Market With Nemluvio Approval

 

Nemluvio is a first-in-class IL-31 inhibitor that the US FDA approved for prurigo nodularis.


Lupin: Glad To Have Dodged Humira Bullet, Lucentis Biosimilar Closer As Phase III Trials Succeed

 
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Lupin’s CEO highlights market access strategy as a key tool to ensure biosimilars success in the US while being relieved the company didn’t launch a Humira biosimilar. She also mentions Amazon and Mark Cuban have not upset market dynamics for generics in the US and a Lucentis biosimilar is closer to a global launch post Phase III trial success

AstraZeneca’s Enhertu Expansion Blocked By NICE Over Price

 

The cost effectiveness watchdog claims AstraZeneca and Daiichi-Sankyo have not offered a fair price for use in the larger HER2-low setting.

BMS ‘Increasingly Confident’ It Can Handle The Impact Of Medicare Pricing For Eliquis

 
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Bristol’s CEO offered assurances about Medicare negotiations under the IRA as the company delivered better-than-expected second quarter results across new and legacy products.

RemeGen Rises, Falls Along With Chinese Antibody Ambitions

 
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Everything seemed to be aligned for success, but shares in leading Chinese antibody developer RemeGen recently dropped by nearly 40%, reflecting a range of internal and external likely factors.


Farxiga Flying Off The Shelf At AstraZeneca

 
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The UK major has raised its full-year sales and earnings forecast on strong demand in the second quarter for its cancer, rare disease and cardiovascular medicines.

China’s Public Payer Challenged To Support Domestic Innovative Drug Market

 

One Chinese biotech executive is entertaining hopes of China’s domestic market for novel drugs growing to CNY300bn ($41bn). However, the country’s public payer spent just CNY90bn on such products in 2023 and is expected to increase expenditure to more than CNY100bn this year.

Rezdiffra Uptake Held Up By Payers, But Not Biopsy Requirements

 
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Several factors are delaying fulfillment of MASH prescriptions, but payers are not holding out for biopsy disease confirmation. KOLs cited by Leerink also call tirzepatide the clear standout in obesity, though access issues are still an issue.

How The IRA Factored Into Akebia’s Price For Vafseo

 

Akebia said it had set the price for Vafseo at about $15,500 per year, meant to reflect its potential value in dialysis as well as eventually in non-dialysis patients.