Following KarXT in Schizophrenia

 
• By Elizabeth Cairns
  
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The FDA is scheduled to pronounce on Bristol Myers Squibb’s potential blockbuster on 26 September. But might forthcoming compounds be more effective?

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• Source: Nielsen Hobbs; the Pink Sheet | Shutterstock image

A US approval decision for Bristol Myers Squibb’s schizophrenia candidate KarXT is approaching fast, and the impressive efficacy the muscarinic M1/ M4 agonist showed in Phase III means the verdict will probably be positive.

Key Takeaways

  • Bristol Myers Squibb’s muscarinic M1/M4 agonist KarXT is likely to be approved for schizophrenia in the US this week.

But several other schizophrenia projects are also speeding through development – some boasting even greater evidence of symptom reduction than...

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