Erenumab Moves Ahead In Treatment-Refractory Migraine in Novartis/Amgen LIBERTY Study

Jan 23 2018

• By John Davis

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Top-line results from the Phase IIIb LIBERTY study are positive regarding primary and secondary endpoints, and could put erenumab ahead of other CGRP antagonists in difficult-to-treat migraine, as this novel class of agents nears the market for migraine prevention.

Headache — Headache and visual disturbances characterize migraine • Source: Shutterstock

With several competing calcitonin gene-related peptide (CGRP) antagonists expected to enter the market over coming months for the prevention of migraine, Amgen Inc. and its collaborator, the Swiss multinational Novartis AG are building what could be compelling evidence of the efficacy of their anti-CGRP monoclonal antibody, Aimovig (erenumab) in difficult-to-treat patients.

Episodic migraine patients who have failed on multiple prior preventive therapies may be one of the categories of migraine sufferers...

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