Price ‘Anchoring’? Zolgensma And The Art Of Managing Gene Therapy Sticker Shock

Public statements by Novartis and Avexis suggest Zolgensma could be cost effective at a price up to $5m. Analysts expect $2m. The lower estimate is still stunning, but could it be considered reasonable by comparison?

Sales problem business concept as a price tag pulling on a heavy anchor as a financial crisis metaphor and slow economy or sluggish retail selling symbol as a 3D illustration icon.

Novartis AG and AveXis Inc. may be following a well-known approach to shaping the public’s reception of the price of their upcoming one-time gene therapy for spinal muscular atrophy, Zolgensma (onasemnogene abeparvovec).

For the first cell and gene therapies, Spark Therapeutics Inc.’s Luxturna (voretigene neparvovec) and Novartis’ Kymriah (tisagenlecleucel), the approach...

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