Novartis AG would have to drop the list price of Fabhalta (iptacopan) for paroxysmal nocturnal hemoglobinuria (PNH) by nearly three quarters to make it more cost-effective, as much of its price is driven by the high prices of the anti-C5 inhibitors used for PNH, according to a new report by the Institute for Clinical and Economic Review (ICER), which also recommended a lower list price for AstraZeneca PLC’s danicopan.
The drug-pricing watchdog posted a revised evidence report assessing the clinical effectiveness and value of Fabhalta and danicopan and plans...






