Scrip-Leadership (Free-2): Titans Of Pharma: Lilly’s Ricks Tops Big Pharma Pay Chart

 
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The big pharma CEO with the highest-valued compensation in 2024 was David Ricks of Eli Lilly, while Pfizer and J&J executives slipped into third and fourth place behind AbbVie's now retired chief Richard Gonzalez. European firms brought up the rear.

As More DLL3 Bispecifics Advance, Doctors Are Adjusting To CRS, ICANS

 
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Amgen’s Imdelltra for small-cell lung cancer is one of two bispecific T-cell engagers approved for solid tumors, but data at the WCLC meeting show other DLL3-targeting BiTEs may be on the way.

Novo Nordisk’s Semaglutide Shows Promise In Hidradenitis Suppurativa

 

An academic study of GLP-1 agonist showed promise in patients with the painful skin condition but with no signs that the Danish drugmaker will pursue the indication, smaller players in the space may be interested.

An Activist Investor Makes A Play For Pfizer

 

Starboard Value has reportedly bought a $1bn stake in Pfizer with an ambition to turn the big pharma around. But growth, not cost cuts, are Pfizer’s challenge.


Executives On The Move: A New CEOs for ACADIA Pharmaceuticals And G1 Therapeutics Among This Week's Changes

 
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​​​<p>Executive Summary​​ </p> ​​<br> <p>Other recent moves in the industry include changes at the top at Adocia, CSL and Entrada Therapeutics.</p>

Executives On The Move: A New CEOs for ACADIA Pharmaceuticals And G1 Therapeutics Among This Week's Changes

 
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​​​<p>Executive Summary​​ </p> ​​<br> <p>Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements</p>

Quick Listen: Scrip's Five Must-Know Things

 
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In this week's podcast edition of Five Must-Know Things: CMS’s price reveal better than expected?; new diabetes risk data for Zepbound; can J&J’s lung cancer combo stand up to Tagrisso?; new recruits for BioMarin leadership; and Glenmark’s shifting revenues.

Executives On The Move: Fulcrum Therapeutics Acquires Chief Commercial Officer From ImmunoGen

 
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Recent moves in the industry include C-suite shuffle at Perspective Therapeutics and Bausch Health, plus Oculis Holding gets a new CDO and Tiziana Life Sciences gets a new CEO.


BioMarin Recruits Amgen R&D’s Friberg, Roche Dealmaker Sabry To Leadership Team

 
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The company, in its new profitable era, is bringing in new leadership, with Amgen VP of medical affairs for rare diseases Greg Friberg and recently retired Roche Partnering head James Sabry.

Executives On The Move: Caribou Biosciences Acquires Chief Medical Officer From Lyell Immunopharma

 
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Recent moves in the industry include changes at the top for Xilio Therapeutics, Zentalis Pharmaceuticals, Beam Therapeutics and Cipher Pharmaceuticals, plus Ardelyx gets a new chief commercial officer.

Syros’s AML Failure Sparks MDS Program Jitters, But Fears May Be Overblown

 

Discontinuation of the AML study created concern about potential readthrough to a pivotal MDS trial, but the company and analysts pointed out differences in the diseases.

Pierre Fabre Pushes To Be Partner Of Choice For Budding Biotechs

 
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Francesco Hofmann, head of R&D at the mid-sized French group, tells Scrip that its strategy of not playing in the spaces that are dominated by big pharma is paying off.


Galderma Gets First Biologic To Market With Nemluvio Approval

 

Nemluvio is a first-in-class IL-31 inhibitor that the US FDA approved for prurigo nodularis.

Korea Q2 Roundup: Hanmi Dispute Simmers, Emerging Obesity Focus

 
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As it reported mixed second-quarter earnings, South Korea's pharma industry is increasingly turning to obesity pipeline assets. Meanwhile, leadership disputes among family members within Hanmi are resurfacing.

Executives On The Move: Six New CEOs Among This Week's Changes

 
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Recent moves in the industry include C-suite shuffles at Valeo Pharma, Xeris Biopharma, ALX Oncology and MEI Pharma, plus BeiGene and Phio Pharmaceuticals get new chief financial officers.  

Executives On The Move: Scancell Holdings Secures Chief Medical Officer From Relief Therapeutics

 
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Recent moves in the industry include C-suite shuffle at Nkarta, plus I-Mab gets a new CEO.  


ProGen’s Dual Agonist Obesity Contender Gains Momentum With Rani Partnership

 
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The CEO of South Korean biotech shares how his company was able to reach a partnership with Rani so quickly and why it is confident in its GLP-1/GLP-2 dual agonist for obesity and diabetes, despite recent disappointing clinical results for its sole rival.

Merck’s Strong Q2 Overshadowed By Gardasil Sales Decline In China

 
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Merck & Co.’s $16.11bn in sales exceeded expectations and prompted a slight increase in 2024 guidance, but HPV vaccine Gardasil came in slightly below consensus due to lower sales in China.

Japan Cell Therapy Hopes Hit By HeartSheet Full Approval Hurdles

 
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Despite initial promise, a novel autologous cell transplant therapy for severe heart failure has faced multiple challenges in gaining full approval in Japan, potentially providing learnings for other developers of regenerative medicines.

Executives On The Move: Four New CMOs And CFOs Among This Week's Changes

 
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Recent moves in the industry include C-suite shuffles at Pulmatrix, Intellia Therapeutics and BridgeBio, while Akeso got a new chief financial officer from Cellectis.