NICE Gives Nucala Initial OK In Severe Asthma After GSK Offers Price Cut

Adult patients with severe eosinophilic asthma in England and Wales look set to get a much needed treatment option following NICE's provisional backing of GlaxoSmithKline's new MAb therapy.

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An undisclosed price discount offered by GlaxoSmithKline PLC has opened the way for severe asthma patients in England and Wales to access Nucala (mepolizumab), the first biologic treatment to target specific white blood cells called eosinophils which are responsible for symptoms in thousands of asthma patients.

The Dec. 1 announcement by the UK HTA reverses NICE's earlier stance when its independent appraisal committee declined to recommend...

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